Analysis of Corticosteroid-Induced Glaucoma Using the Japanese Adverse Drug Event Reporting Database

Glaucoma is the most common cause of blindness, which significantly reduces quality life. Most glaucoma cases are primary glaucoma; nevertheless, many patients suffer from caused by drugs, such as corticosteroids. A comprehensive review risks associated with corticosteroid-induced limited. Therefore, we used Japanese Adverse Drug Event Reporting Database (JADER) published Pharmaceuticals and Medical Devices Agency (PMDA) to analyze risk factors trends characteristics glaucoma. We did not find sex or age differences onset Hierarchical clustering principal component analysis revealed that triamcinolone acetonide betamethasone sodium phosphate, around eyes in Japan, more likely induce intraocular pressure (IOP) elevation compared other Increased IOP a direct Based on these findings, it may be necessary limit avoid use